IL-10 and TNF-α polymorphisms in subjects with irritable bowel syndrome in Mexico

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BACKGROUND/AIMS The aim of this study was to investigate whether genetic variations at positions -1082, -819, and -592 in the interleukin (IL)-10 promoter affect IL-10 production in children with irritable bowel syndrome (IBS). METHODS Ninety-four children with IBS and 102 children as healthy controls (HCs) were enrolled. Genomic DNA was extracted, and IL-10 -1082, -819, and -592 polymorphism...

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ژورنال

عنوان ژورنال: Revista Española de Enfermedades Digestivas

سال: 2013

ISSN: 1130-0108

DOI: 10.4321/s1130-01082013000700004